Noé Brasier MD is a medical doctor by training with a board certification in internal medicine from FMH. His research focuses on the translation of wearable body-fluid analysis, with a focus on sweat, into clinical application. Wearable body-fluid analysis is a promising novel approach to revolutionize patient care by enabling a continuous, mostly non-invasive, and lab-independent biochemical monitoring of health and disease. Noé graduated from MedSchool of the University of Basel, Switzerland, in 2015 and received his medical doctoral degree in 2018 from the University of Basel. After concluding his clinical training in internal medicine in 2021, he was awarded a MedLab Fellowship by the ETH Zurich, where he continued his research work at the Institute of Translational Medicine. In his actual role as early-career fellow at the Collegium Helveticum, Noé is further developing the field of translational sweat analysis.

Sweating is an essential physiological function for maintaining thermoregulatory homeostasis by dissipating heat from the body. It indicates emotional stress in a social context and sweat holds a lot of biochemical information about the body. Analyzing and assessing sweat has been challenging, as gold standards require laborious sample procedures and specialized labs. The emergence of next-generation wearable devices for sweat analysis promises to revolutionize patient care by enabling non-invasive, lab-independent, continuous biochemical monitoring remotely. However, as the technology is still early in development, multiple challenges remain to make these devices ready for clinical application. These challenges include understanding the physiology of sweating, developing clinical concepts to implement these devices, understanding the needs of various stakeholders in healthcare, and setting up clinical studies to prove added clinical value. This lecture will address the following topics: (i) introduction to sweat as a diagnostic body fluid, (ii) introduction to wearable sweat sensing and why context information is essential, (iii) clinical concepts in wearable sweat analysis, (iv) stakeholders involved, and finally, (v) the direction of wearable sweat analysis.

Prof. Dr. Tobias Kowatsch, Associate Professor for Digital Health Interventions, Institute for Implementation Science in Health Care, University of Zurich; Director, School of Medicine, University of St.Gallen (HSG); Scientific Director, Centre for Digital Health Interventions (CDHI), ETH Zurich & HSG; Principal Investigator, Future Health Technologies programme, Campus for Research Excellence and Technological Enterprise (CREATE), Singapore-ETH Centre, Singapore

Prof. Dr. Elgar Fleisch, Professor of Information Management, ETH Zürich; Professor of Technology Management, University of St.Gallen; Advisory Board Member, CDHI, ETH Zürich & University of St.Gallen; Principal Investigator, Future Health Technologies programme, Campus for Research Excellence and Technological Enterprise (CREATE), Singapore-ETH Centre, Singapore

Prof. Dr. Florian von Wangenheim, Professor of Technology Marketing, ETH Zurich & Advisory Board Member, CDHI; Principal Investigator, Future Health Technologies programme, Campus for Research Excellence and Technological Enterprise (CREATE), Singapore-ETH Centre, Singapore