At the 49th Annual Meeting of the Society for Neuropediatrics in Stuttgart, our research assitant Marc-Robin Grüner and PD Dr. med. Philip Julian Broser the Children’s Hospital of Eastern Switzerland presented their work on diabetic peripheral neuropathy (DPN) in pediatric Type 1 Diabetes (T1D). The research introduces the Glucose Fluctuation Moments Index (GFMI), a digital biomarker developed to assess the impact of glucose fluctuations on nerve conduction velocity (NCV) in young T1D patients. The presented prospective study, conducted at the Children’s Hospital of Eastern Switzerland with 17 T1D patients, examined the correlation between various glucose variability metrics and deviations from expected height-adjusted NCV values (dNCV). Statistical analysis showed that GFMI correlates with dNCV in the peroneal nerve (r = -0.54, p = 0.01), compared to established metrics such as Standard Deviation (r = -0.39) and Average Daily Risk Range (r = -0.35). These findings suggest potential applications in the evaluation of diabetes treatment regimens and development of insulin dosing algorithms. This work is part of the KIND project, which investigates the relationship between glucose fluctuations and nerve vitality in children with T1D. The project employs systematic data collection from continuous glucose monitoring systems, clinical labs, and nerve conduction studies. The research team continues to study the physiological mechanisms underlying DPN progression in young diabetes patients.